Retinal layers thickness and vascular density analysis based on optical coherence tomography angiography after successful scleral buckle
Mohammadreza Niyousha1 *, narges Hassanpoor10
- Tabriz university of medical sciences, Nikookari eye hospital
Abstract: To investigate retinal layers thickness and vascular density analysis based on optical coherence tomography angiography after successful scleral buckle
Methods: The study is a prospective interventional case-control study in which 24 patients with macula off rhegmatogenous retinal detachment were included after successful reattachment by scleral buckling. Retinal layers thickness and vasculature were compared using optical coherence tomography angiography with normal fellow eye as control 10 months post operation
Results: Inner retinal layers showed no significant difference. Significant reduction in outer 1mm central retinal layers thickness was evident. Outer plexiform- Bruch’s membrane ( 153 ± 24.3 µm vs 166 ±15.1 µm , P value = 0.003) and ellipsoid zone (inner segment-Outer segment junction) to Bruch’s membrane ( 51.25± 9.3 µm vs 57.35 ± 3.8 µm, P value = 0.009) were thinner in operated eyes compared to fellow eyes .Vascular density in a 300μm wide region around foveal avascular zone (FD-300) was significantly reduced in detached eyes (46 ± 7 % vs 51 ± 4 % , P value = 0.016), however there was no difference in foveal 1mm central superficial and deep vascular density. Superficial parafoveal vascular density was lower in operated eyes (46 ± 5% vs 49 ± 6% , P value= 0.026) but deep parafoveal vascular density was not significantly different between operated and control eyes. There was no difference in foveal avascular zone area and perimeter between two groups.
Conclusion: Full recovery of retinal thickness and vascular density did not achieve in rhegmatogenous retinal detachment patients even after 10 months of reattachment by scleral buckling surgery
