Comparison of 3 silicone hydrogel bandage soft contact lenses on postoperative pain control and epithelial healing time after photorefractive keratectomy

Ali Ayatollahi1 *, Saeid Abdi1 , Mohsen Mirzaei2

  1. Department of Optometry, School of Rehabilitation, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  2. Optometrist

Abstract: The purpose of this study was to compare the Senofilcon A, Lotrafilcon B and Balafilcon A contact lenses on postoperative pain control and epithelial healing time after photorefractive keratectomy (PRK)

Methods: 96 patients (189 eyes) with a spherical equivalent ≤-4.50 diopter that having photorefractive keratectomy were randomized to a senofilcon A, lotrafilcon A and balafilcon A bandage contact lenses in each eye postoperatively. ocular symptoms of Pain, blurred vision, epiphora, photophobia, and foreign body sensation were evaluated by questionnaire on days 1, 3, and 6 postoperatively. The healing time of the corneal epithelium was also assessed.

Results: At 1, 3, and 6 days, eyes with the senofilcon A lens had the lowest pain scores followed by eyes with the balafilcon A lens and then eyes with the lotrafilcon A lens. The mean score of foreign body sensation was 4.32, 5.47, and 5.63 on the first day, 4.12, 5.24, and 5.19 on the third day, and 2.89, 3.11, and 3.04 on the sixth day after the use of the senofilcon A, lotrafilcon B, and comfilcon A, respectively. There was no statistically significant difference between groups in terms of photophobia, blurred vision, and epiphora (P > 0.05). epithelial healing was complete in 52 eyes (82.4%) with senofilcon A lenses, 53 eyes (83.2%) with balafilcon A lenses, and 56 eyes (87.3%) with lotrafilcon B lenses.

Conclusion: Duration of corneal epithelial healing after PRK between the three contact lenses did not differ significantly. There was a clinically significant difference in post-photorefractive keratectomy pain between the 3 bandage contact lenses. The senofilcon A lens caused the least pain.





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