Expanded Spectrum of EDI-OCT in patients with ocular toxoplasmosis
Nazanin Ebrahimiadib1 *, Kaveh Fadakar2 , Mohammad Zarei2
- Tehran University of Medical Sciences
- TUMS
Abstract: To describe the enhanced depth imaging optical coherence tomography (EDI-OCT) findings of toxoplasmic retinochoroiditis lesions at different stages of activity.
Methods: In this observational case series, medical records and EDI-OCT findings of patients diagnosed with ocular toxoplasmosis were reviewed.
Results: Thirty-two eyes of 31 patients were included; 43 sets of OCT images were reviewed. For six patients, follow up photographs were available. Fourteen lesions were classified as active, 16 as inactive and 13 were partially active. All active lesions demonstrated increased retinal thickness and reflectivity with blurring of the details of the retinal layers. Granuloma and hypo-reflectivity of the underlying choroid were detected in 8 (61.5%) eyes with active features. Serous retinal detachment was present in 9 (64%) eyes with active lesions. Scarified lesions showed decreased retinal and choroidal thickness with moderate hyper-reflectivity. Signs of decreased activity of the lesion including RPE-Bruch’s membrane splitting and characteristic hourglass configuration were observed in 8 (50%) of inactive lesions with either elevated or dimpled shaped scars. In partially active lesions, sustained thickening and/or attachment of posterior hyaloid face with fine epiretinal membrane formation was the hallmark.
Conclusion: Features in EDI-OCT images are helpful to specify the inflammatory activity of toxoplasmic retinochoroiditis lesions and monitoring their response to treatment.
