Determination of the Mechanical Properties of Human Cornea Using an Anisotropic Hyper-Viscoelastic Model and Coupled Finite Element-Optimization Analysis
Farideh Doroodgar, MD1 *, Sana Niazi, MS2 , Milad Mahdian3
- Negah Eye Hospital Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
- Department of Ophthalmology, Shahid Beheshti University of Medical Sciences and Health Services, Tehran, Iran
- Department of Mechanical Engineering, Khomeinishahr Branch, Islamic Azad University, Khomeinishahr/Isfahan, Iran
Abstract: Determination of the Mechanical Properties of Human Cornea
Methods: In this study, eight material parameters of the structural anisotropic fiber-reinforced hyper visco-elastic model of Cornea with various fiber angles (8, 18, 22.5, and 45 degrees) have been obtained using coupled finite element-optimization analysis and experimental data. The utilized model considers the dispersion of the fibers along with their reorientation during loading, the nonlinear behavior of finite tissue deformation, and the intrinsic viscoelastic property of the matrix. The effect of each parameter on the sample responses in the tensile test simulation was examined.
Results: The results demonstrated that the J-shape behavior of the samples under the tensile test can be justified by the model used in the present study. Examining the results shows that the numerical simulations performed for the prediction of the cornea tissue behavior are nearly consistent with the experimental results, and have good accuracy and that the model has acceptable stability.
Conclusion: The numerical simulations performed for the prediction of the cornea tissue behavior are nearly consistent with the experimental results, and have good accuracy, and that the model has acceptable stability.
